Well my female lab tested positive for heart worms last fall. The vet suggested I wait till after the season to begin treatment (this was her first hunting season). Today she recieved her first shot for the fast kill method. She is week and sore from sedation. Any one with experience that can tell me real life experience what to expect for the next few months? I know she will have to be relaxed in her kennel through the duration. Luckily we cuaght it at a young age and the pharm company is covering the treatment. She was on Heartworm preventatives since day one. The vet informed us missippi, Louisiana and coastal nc have mosquitos who acarry heart worms immune to modern meds. Wish us luck!