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Discussion in 'The Duck Hunters Forum' started by sdkidaho, May 21, 2020.
Or what I called that big fat greenhead when I whiffed 3 shots on him
Not necessarily. In most cases, we do develop active immunity against that bug, but sometimes we do not. A basic introduction to innate and active immunity may help explain this.
When the body is exposed to a pathogen or foreign substance, we have defense systems in our body which will fight, in a general, non-specific way, the infection. Our host body defenses will be attempting to fight off a "bug" which it sees as foreign and as such, will try to get rid of it. This general response is called innate immunity, and is a common defense that we all put up to the "bug". This includes physical barriers (layers of the skin), and a series of circulating cells which respond to trauma or foreign matter, including NK (natural killer) cells, macrophages , neutrophils, complement protein etc. ) These responses generally occur with any infection.
This gives us our first defence against the infection. Some of the infective bugs are either presented to, or come into contact with cells of the adaptive defence system. These cells produce specific antibodies against specific parts of the "bug" which are generally specific to that organism. Once the infection is cleared, the body will still produce cells/antibodies circulate so if you are exposed a second time, the response is more immediate and more pronounced, hence a "secondary" response.
This is why the first time you roll in the poison ivy, you may have a mild rash or irritation for a few days. Your immune system is busy producing antibodies and cellular responses, so that 3 months from now, you roll around in the poison ivy, you then swell up immediately and have a severe allergic reaction.
This is called the secondary or amanestic (sp.?) response.
With COVID-19, none of us had experienced this bug before, so our responses tend to be of the innate type, but hopefully we will produce antibodies to prevent recurrent infections (secondary response). This is the idea with vaccines.
With vaccines, there are 4 or 5 different types available (I posted on another thread here). Some use whole virus, broken down virus, surface proteins and structures, or a unique mRNA virus which actually gets our cells to program the antibodies. Are these better or worse than natural immunity? It truly is hard to say. Sometimes the use of adjuncts will stimulate the body's immune system to higher levels than a natural infection will, and vice versa is true as well. Some vaccines work better with inactivated whole virus, some are just fine with virus "parts" or "haptens". Then we have individual variations as well. As we get older, our immune system begins to fail us, and we are more susceptible to infection, and slower at making antibodies, which may be a lower "titre" or at a lower level which may not be able to fight off an aggressive organism.
With certain bugs, like Herpes zoster, getting shingles does not prevent you from getting it again. The secondary response of our body is poor, and your natural immunity may not be enough to treat or prevent it, and you would benefit from getting the shingles vaccine series,which boosts your antibody levels high enough to prevent a further attack. This problem is mainly in older adults, and the shingles vaccine is recommended fo ages 50 and older, targeting us old farts.
The above is the basic way I was taught and the theory has been now challenged by a more adaptive innate immunity, but basically , future responses become more rapid and at a higher level of response in future challenges. The new term is "Trained" innate immunity, but the results are similar.
pretty much what he said. this whole gd thing still smells like fish to me.
Couldn’t every post have this same response?
What business is it of yours if they do or not?
Nope. Not even close
It’s a valid question. Mods are allowed to troll here.
Nothing anyone thinks on this forum is any business of mine unless they choose it to be.
Is 'infection' showing symptoms or having the virus in your system?